TEXT ON SCREEN: Ask Me Anything Anytime, Anywhere with Traci

SUPER: UBRELVY is a prescription medicine used for the acute treatment of migraine attacks with or without aura in adults. UBRELVY is not used to prevent migraine headaches

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: So what would a migraine attack sound like on a saxophone?

TRACI: (TRACI plays a long note) That’s pretty good!

SUPER: UBRELVY is a prescription medicine used for the acute treatment of migraine attacks with or without aura in adults. UBRELVY is not used to prevent migraine headaches

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: So what are we doing here?

TRACI: So, today I have practice with my jazz ensemble.

SUPER: Traci is an actual UBRELVY patient who was on prescribed therapy when she provided this testimonial. Changes in therapy status may have occurred since that time. Traci was compensated for sharing her story.

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: How have migraine attacks affected your ability to play?

TRACI: Wow. The pressure of me blowing the air into this instrument. It just makes the pain even more intense. So, it’s horrible.

SUPER: IMPORTANT SAFETY INFORMATION

Do not take UBRELVY if you are taking medicines known as strong CYP3A4 inhibitors, such as ketoconazole, clarithromycin, or itraconazole, or if you are allergic to UBRELVY or any of its ingredients.

SUPER: Keep watching for additional Important Safety Information.

TRACI: I was 19 when I had my first migraine attack. It will start in my right eye, of like a deep, throbbing pain. And it just cruises around the entire back of my head until it lands in the left eye. And then from there, it’s just like my whole head is just pounding.

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: Do you have UBRELVY with you right now?

TRACI: I do. I never leave without UBRELVY! I am so thankful that I found UBRELVY.

SUPER: In clinical trials, UBRELVY provided pain freedom within 2 hours. Individual results may vary.

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: What are your early signs of a migraine attack that come before head pain?

TRACI: I experience light sensitivity. I have a lot of pain in my neck. When I do have the early signs, I can take my UBRELVY. If someone is out there that is suffering from a migraine attack, I would highly suggest that they speak with their doctor about trying UBRELVY.

SUPER: In a separate phase 3 clinical trial, people studied were able to reliably predict a headache 1-6 hours before it started. Not everyone has pre-headache symptoms; some studied couldn’t accurately predict their headaches. Talk to your doctor about early signs of a migraine attack.

SUPER: Keep watching for Important Safety Information.

SAFETY AVO:

What is UBRELVY® (ubrogepant)?

UBRELVY is a prescription medicine used for the acute treatment of migraine attacks with or without aura in adults. UBRELVY is not used to prevent migraine headaches.

IMPORTANT SAFETY INFORMATION

Do not take UBRELVY if you are taking medicines known as strong CYP3A4 inhibitors, such as ketoconazole, clarithromycin, or itraconazole, or if you are allergic to UBRELVY or any of its ingredients.

Before taking UBRELVY, tell your healthcare provider about all your medical conditions, including if you:

• Have high blood pressure
• Have circulation problems in your fingers and toes
• Have liver problems
• Have kidney problems
• Are pregnant or plan to become pregnant
• Are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Your healthcare provider can tell you if it is safe to take UBRELVY with other medicines.

UBRELVY may cause serious side effects, including:

• Allergic reactions: Most reactions happened within hours after taking UBRELVY and were not serious. Some reactions may occur days after taking UBRELVY. Call your healthcare provider or get emergency help right away if you have swelling of the face, mouth, tongue, or throat or trouble breathing.
• High blood pressure: New or worsening of high blood pressure can happen. Contact your healthcare provider if you have an increase in blood pressure.
• Raynaud’s phenomenon: A type of circulation problem can worsen or happen. Raynaud’s phenomenon can lead to your fingers or toes feeling numb, cool, or painful, or changing color from pale, to blue, to red. Contact your healthcare provider if these symptoms occur.

The most common side effects of UBRELVY are nausea (4%) and sleepiness (3%). These are not all of the possible side effects of UBRELVY.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/PatientAccessSupport to learn more.

Please see full Patient Information at UBRELVY.com or visit www.rxabbvie.com/pdf/ubrelvy_pil.pdf.