TEXT ON SCREEN: Ask Me Anything Anytime, Anywhere with Laura

SUPER: UBRELVY is a prescription medicine used for the acute treatment of migraine attacks with or without aura in adults. UBRELVY is not used to prevent migraine headaches

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: What’s the plan for tonight?

LAURA: We’re gonna have book club with the ladies! (Laura laughs)

SUPER: UBRELVY is a prescription medicine used for the acute treatment of migraine attacks with or without aura in adults. UBRELVY is not used to prevent migraine headaches

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: Have you changed plans because of a migraine attack?

LAURA: Yeah, I've had to cancel for sure. I feel like migraine attacks have taken away a lot. I am not someone who calls out of work, but I would go, and um it would be very hard to be there.

SUPER: Laura is an actual UBRELVY patient who was on prescribed therapy when she provided this testimonial. Changes in therapy status may have occurred since that time. Laura was compensated for sharing her story.

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: When were you diagnosed with migraine and what treatments have you tried?

LAURA: It was not until I was in my twenties when I went to the doctor and started to get more treatment for migraine.

SUPER: IMPORTANT SAFETY INFORMATION

Do not take UBRELVY if you are taking medicines known as strong CYP3A4 inhibitors, such as ketoconazole, clarithromycin, or itraconazole, or if you are allergic to UBRELVY or any of its ingredients.

SUPER: Keep watching for additional Important Safety Information.

LAURA: I started getting headaches when I was I think like, 12 or 13. I've tried several over-the-counter medications, triptans, I had a patch on my arm, so I feel like I've tried a lot of things. When I talked to my doctor, I would talk to them about other medications that I tried.

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: Do you keep UBRELVY on you at all times?

LAURA: I keep it in my work bag. I keep it in my regular bag. I even have it with me right now.

SUPER: In clinical trials, patients took UBRELVY within 4 hours of a migraine attack.

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: What would you tell others about UBRELVY?

LAURA: I would be like, this is what I use and you should ask your doctor about it.

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: When did you first start taking UBRELVY?

LAURA: I first started taking it a few years ago. It works. I know that I'll take it and within two hours that my migraine will start to go away. I definitely feel like I'm able to keep going even when I have a migraine attack.

SUPER: Can provide pain freedom within 2 hours. Individual results may vary.

SUPER: Keep watching for Important Safety Information.

TEXT ON SCREEN/DIRECTOR VO: Are the girls almost here?

LAURA: They are almost here. And so that means that you better go soon.

SUPER: Keep watching for Important Safety Information.

DIRECTOR & CREW: You did great, that’s a wrap!

SAFETY AVO:

What is UBRELVY® (ubrogepant)?

UBRELVY is a prescription medicine used for the acute treatment of migraine attacks with or without aura in adults. UBRELVY is not used to prevent migraine headaches.

IMPORTANT SAFETY INFORMATION

Do not take UBRELVY if you are taking medicines known as strong CYP3A4 inhibitors, such as ketoconazole, clarithromycin, or itraconazole, or if you are allergic to UBRELVY or any of its ingredients.

Before taking UBRELVY, tell your healthcare provider about all your medical conditions, including if you:

• Have high blood pressure
• Have circulation problems in your fingers and toes
• Have liver problems
• Have kidney problems
• Are pregnant or plan to become pregnant
• Are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Your healthcare provider can tell you if it is safe to take UBRELVY with other medicines.

UBRELVY may cause serious side effects, including:

• Allergic reactions: Most reactions happened within hours after taking UBRELVY and were not serious. Some reactions may occur days after taking UBRELVY. Call your healthcare provider or get emergency help right away if you have swelling of the face, mouth, tongue, or throat or trouble breathing.
• High blood pressure: New or worsening of high blood pressure can happen. Contact your healthcare provider if you have an increase in blood pressure.
• Raynaud’s phenomenon: A type of circulation problem can worsen or happen. Raynaud’s phenomenon can lead to your fingers or toes feeling numb, cool, or painful, or changing color from pale, to blue, to red. Contact your healthcare provider if these symptoms occur.

The most common side effects of UBRELVY are nausea (4%) and sleepiness (3%). These are not all of the possible side effects of UBRELVY.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/PatientAccessSupport to learn more.

Please see full Patient Information at UBRELVY.com or visit www.rxabbvie.com/pdf/ubrelvy_pil.pdf.